St Edmund Hall Chapel
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Talks II: Chapel

Seeing the Invisible in Health and Disease

Keith Gull (SCR)

Read more > The development of the electron microscope in the middle of the last century revolutionised biology and our understanding of cells and tissues. Developments have continued and in this century computation methods have enabled 3D imaging of complete cells. I will show, using images of diverse cells and life forms, how our ability to now see the invisible is central to research in biology – from infectious disease to cancer and Alzheimers.  

Shakespeare's Animals

Tom MacFaul (SCR)

Read more >Only two actual animals definitely appear in Shakespeare’s plays: a naughty dog in The Two Gentlemen of Verona and a hungry bear in The Winter’s Tale. But animals are everywhere in Shakespeare’s language. This talk will offer some suggestions as to why that is, and will show that the much-vaunted idea of human specialness in the Renaissance was highly precarious.

Current practice in preventing and handling missing data alongside clinical trials: are we doing well?

Ines Rombach (MCR)

Read more >Missing data is present in almost all research. However, it is also a well-recognised problem in the analysis and reporting of clinical research due to its potential to introduce bias into the results. Patient-reported outcomes measures, which are increasingly used in clinical research, can be particularly susceptible to missing data. This presentation will review the methodology surrounding missing data in research and statistical analysis, clarifying why it can contribute to misleading results. Guidance for the handling and reporting of missing data in clinical research will be presented, and compared to current practice, with a focus on randomised controlled trials.

Past and Future Earthquake Hazard in Asia

Richard Walker (SCR)

Read more >Mongolia, Kazakhstan, and Kyrgyzstan are lands of high mountains, faults, and earthquakes in the heart of Asia. The active deformation is due to the collision of India and Asia, which has generated faulting and mountain-building covering a region stretching from the Himalaya to Siberia, and is one of the main testing-grounds for theories of continental tectonics. A feature of many of the regions in which mountains are forming at the present-day - including central Asia - is that they are situated hundreds, or even thousands, of kilometres away from plate boundaries. As well as causing a widespread hazard to local populations, the very wide distribution of faulting within the continents show that they behave rather differently from oceanic plates, in which relative plate motions are accommodated within very narrow plate boundary zones. We still do not understand the rules that govern the distribution, in space and time, of major episodes of mountain building; but an essential first step in understanding these rules, which remains one of the fundamental goals in the study of continental tectonics, is to provide constraints on the distribution, rates, and evolution of deformation.

In this lecture, Richard will describe some of his travels in central Asia, and will show the ways in which the landscape has been influenced by active faults and earthquakes. He will give examples of earthquakes from history and from prehistory, and will examine the hazard faced at the present-day.