Dr Katherine Wright

College Lecturer in Biochemistry

Kate is a College Lecturer in Biochemistry at St Edmund Hall. Her research interests include host-parasite interactions and malaria.

1: Wright KE, Hjerrild KA, Bartlett J, Douglas AD, Jin J, Brown RE, Illingworth JJ, Ashfield R, Clemmensen SB, de Jongh WA, Draper SJ, Higgins MK. Structure of malaria invasion protein RH5 with erythrocyte basigin and blocking antibodies. Nature. 2014 Nov 20;515(7527):427-30.

2: Hjerrild KA, Jin J, Wright KE, Brown RE, Marshall JM, Labbé GM, Silk SE, Cherry CJ, Clemmensen SB, Jørgensen T, Illingworth JJ, Alanine DG, Milne KH, Ashfield R, de Jongh WA, Douglas AD, Higgins MK, Draper SJ. Production of full-length soluble Plasmodium falciparum RH5 protein vaccine using a Drosophila melanogaster Schneider 2 stable cell line system. Sci Rep. 2016 Jul 26;6:30357.

3: Campeotto I, Goldenzweig A, Davey J, Barfod L, Marshall JM, Silk SE, Wright KE, Draper SJ, Higgins MK, Fleishman SJ. One-step design of a stable variant of the malaria invasion protein RH5 for use as a vaccine immunogen. Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):998-1002.

4: Jin J, Hjerrild KA, Silk SE, Brown RE, Labbé GM, Marshall JM, Wright KE, Bezemer S, Clemmensen SB, Biswas S, Li Y, El-Turabi A, Douglas AD, Hermans P, Detmers FJ, de Jongh WA, Higgins MK, Ashfield R, Draper SJ. Accelerating the clinical development of protein-based vaccines for malaria by efficient purification using a four amino acid C-terminal ‘C-tag’. Int J Parasitol. 2017 Jun;47(7):435-446.

5: Koch M, Wright KE, Otto O, Herbig M, Salinas ND, Tolia NH, Satchwell TJ, Guck J, Brooks NJ, Baum J. Plasmodium falciparum erythrocyte-binding antigen 175 triggers a biophysical change in the red blood cell that facilitates invasion. Proc Natl Acad Sci U S A. 2017 Apr 18;114(16):4225-4230.

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Biochemistry (Molecular and Cellular)

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