Professor David Dupret

• MRC Investigator, Brain Network Dynamics Unit, Nuffield Department of Clinical Neurosciences
• Professor of Neuroscience, University of Oxford
• Tutorial Fellow in Neuroscience, St Edmund Hall
• Scholar of the FENS-Kavli Network of Excellence
• “Professeur Agrégé ès Sciences Biologiques”, French Ministry of Education (currently on leave)

Professor Dupret’s research interests address the temporal dynamics of brain circuits in relation to behaviour. The primary aim of his research programme is to understand how neuronal activity in the hippocampal circuit contributes to the acquisition, consolidation and recall of memory traces.

More information about the Dupret Group

Recent Articles

Barron HC, Mars RB, Dupret D, Lerch J, Sampaio-Baptista C. Cross-species neuroscience: closing the explanatory gap. Philos Trans R Soc Lond B Biol Sci. 2021 Jan 4;376(1815):20190633

Barron H.C., Reeve H.M, Koolschijn R.S., Perestenko P.V., Shpektor A., Nili H., Rothaermel R., Campo-Urriza N., O’Reilly J.X., Bannerman D.M., Behrens T.E.J. and Dupret D. Neuronal computation underlying inferential reasoning in humans and mice. Cell. 2020 Oct 1;183(1):228-243.

Trouche S, Koren V, Doig NM, Ellender TJ, El-Gaby M, Lopes-Dos-Santos V, Reeve HM, Perestenko PV, Garas FN, Magill PJ, Sharott A and Dupret D. A Hippocampus-Accumbens Tripartite Neuronal Motif Guides Appetitive Memory in Space. Cell. 2019 Mar 7;176(6):1393-1406.

Lopes-dos-Santos V, van de Ven GM, Morley A, Trouche S, Campo-Urriza N and Dupret D. Parsing hippocampal theta oscillations by nested spectral components during spatial exploration and memory-guided behavior. Neuron. 2018 Nov 21;100(4):940-952.

Joshi A, Salib M, Viney TJ, Dupret D, Somogyi P. Behavior-dependent activity and synaptic organization of septo-hippocampal GABAergic neurons selectively targeting the hippocampal CA3 area. Neuron. 2017 Dec 20;96(6):1342-1357.

McNamara CG, Dupret D. Two sources of dopamine for the hippocampus. Trends Neurosci. 2017 May 13.

van de Ven GM, Trouche S, McNamara CG, Allen K, Dupret D. Hippocampal Offline  Reactivation Consolidates Recently Formed Cell Assembly Patterns during Sharp Wave-Ripples. Neuron. 2016 Dec 7;92(5):968-974.

Trouche S, Perestenko PV, van de Ven GM, Bratley CT, McNamara CG, Campo-Urriza N, Black SL, Reijmers LG, Dupret D. Recoding a cocaine-place memory engram to a neutral engram in the hippocampus. Nat Neurosci. 2016 Apr;19(4):564-7.

Vidaurre D, Quinn AJ, Baker AP, Dupret D, Tejero-Cantero A, Woolrich MW. Spectrally resolved fast transient brain states in electrophysiological data. Neuroimage. 2016 Feb 1;126:81-95.

Atherton LA, Dupret D, Mellor JR. Memory trace replay: the shaping of memory consolidation by neuromodulation. Trends Neurosci. 2015 Sep;38(9):560-70.

McNamara CG, Tejero-Cantero Á, Trouche S, Campo-Urriza N, Dupret D. Dopaminergic neurons promote hippocampal reactivation and spatial memory persistence. Nat Neurosci. 2014 Dec;17(12):1658-60.

Dupret D, Csicsvari J. Turning heads to remember places. Nat Neurosci. 2014 May;17(5):643-4.

Csicsvari J, Dupret D. Sharp wave/ripple network oscillations and learning-associated hippocampal maps. Philos Trans R Soc Lond B Biol Sci. 2013 Dec 23;369(1635):20120528.

Dubruc F, Dupret D, Caillard O. Self-tuning of inhibition by endocannabinoids shapes spike-time precision in CA1 pyramidal neurons. J Neurophysiol. 2013 Oct;110(8):1930-44.

Dupret D, O’Neill J, Csicsvari J. Dynamic reconfiguration of hippocampal interneuron circuits during spatial learning. Neuron. 2013 Apr 10;78(1):166-80.

Dupret D, Csicsvari J. The medial entorhinal cortex keeps Up. Nat Neurosci. 2012 Nov;15(11):1471-2.

Dupret D, Pleydell-Bouverie B, Csicsvari J. Rate remapping: when the code goes beyond space. Neuron. 2010 Dec 22;68(6):1015-6.

Dupret D, O’Neill J, Pleydell-Bouverie B, Csicsvari J. The reorganization and reactivation of hippocampal maps predict spatial memory performance. Nat Neurosci. 2010 Aug;13(8):995-1002.

O’Neill J, Pleydell-Bouverie B, Dupret D, Csicsvari J. Play it again: reactivation of waking experience and memory. Trends Neurosci. 2010 May;33(5):220-9.

Revest JM, Dupret D, Koehl M, Funk-Reiter C, Grosjean N, Piazza PV, Abrous DN. Adult hippocampal neurogenesis is involved in anxiety-related behaviors. Mol Psychiatry. 2009 Oct;14(10):959-67.

Dupret D, Pleydell-Bouverie B, Csicsvari J. Inhibitory interneurons and network oscillations. Proc Natl Acad Sci USA. 2008 Nov 25;105(47):18079-80.

Textbook

Dupret D. Molecular and Cell Biology Handbook « L’état pluricellulaire », Ellipse Ed. 2003